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KMID : 1157520140100020109
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International Journal of Clinical Preventive Dentistry
2014 Volume.10 No. 2 p.109 ~ p.112
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Polymer Effect on Antimicrobial Agents Used inDentifrices
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Yoo Su-Min
Hwang Kyung-Sook
Ahn Geum-Sun
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Abstract
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Objective: In this study, the anti-microbial effects of cetylpyridinium chloride (CPC), chlorhexidine, and polymer-combined CPC were compared as a bioactive component of dentifrices.
Methods: Hydroxyapatite disks were coated with 1% mucin for 30 minutes and then OD (optical density) values were meas-ured in order to compare the antimicrobial effects of CPC, chlorhexidine and polymer-combined CPC.
Results: The OD values of chlorhexidine and polymer-combined CPC treated sample showed statistically significant anti-microbial effects compared with CPC in dentifrices (p＜0.05). Especially, polymer-combined CPC showed most effective for inhibition of Streptococcus mutans.
Conclusion: The antimicrobial activity of CPC was enhanced by combining polymer in dentifrices.
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KEYWORD
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antibacterial agents, cetylpyridinium, chlorhexidine, dentifrices, polymers
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